Michigan Center for Regenerative Medicine

Michigan Center for Regenerative Medicine

Intraosseous Treatment in MichiganTreating the bone beneath an arthritic joint

An advanced, image-guided option for knee and hip arthritis from board-certified physicians at our Rochester Hills and Grand Rapids offices.

★ 4.7 Google rating · Board-certified physicians · Rochester Hills & Grand Rapids

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What are intraosseous injections?

Intraosseous treatment places regenerative treatment into the joint and directly into the bone beneath it, to help support the cartilage from the inside out. At the Michigan Center for Regenerative Medicine, this outpatient procedure may be an option for more severe knee and hip osteoarthritis, giving some patients another non-surgical choice before joint replacement.

Most regenerative joint treatments place cells or platelets inside the joint. Intraosseous treatment goes one step further: your physician places treatment both into the joint and into the bone just beneath the cartilage. The bone under a worn joint surface is often involved in arthritis pain, so treating it may help support the joint from the inside out.

How Intraosseous Treatment Works

Modern procedure room with C-arm imaging

Cartilage rests on a layer of bone. In advanced arthritis, that bone can become damaged and painful too. Intraosseous treatment delivers regenerative treatment, such as a concentrate of your own bone marrow cells, to that bone as well as the joint space. Precise placement matters, so it is done with x-ray guidance by physicians trained in interventional procedures.

Possible Benefits

  • Treats the bone under the cartilage as well as the joint, which may help more advanced knee and hip arthritis.
  • Another non-surgical option for some patients who were told their only choice was joint replacement.
  • Outpatient procedure: you go home the same day.
  • Shorter recovery than joint replacement surgery, with a period of limited weight bearing afterward.
  • Keeps future options open, since it does not use up the joint the way a replacement does.

Who May Be a Candidate?

We currently use intraosseous treatment for knee and hip pain, often for more severe osteoarthritis. It is a more involved procedure than a joint injection, and it is not right for everyone. Results vary, and some patients will still need joint replacement. Your physician will review your imaging and explain whether it fits.

Our physicians have extensive training in interventional pain management, which is critical for accurate placement. Learn more in intraosseous treatment compared to surgery and stem cell therapy and hip replacement.

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Conditions

Conditions We Evaluate

Intraosseous treatment is currently used for knee and hip arthritis, often when arthritis is more advanced.

Knee Osteoarthritis

More advanced knee arthritis, including bone changes beneath the cartilage.

Hip Osteoarthritis

Hip arthritis when joint injections alone may not be enough.

Bone Marrow Lesions

Painful changes in the bone under a worn joint surface, seen on MRI.

Patient reviews

What Our Patients Say

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Gwendolyn Botardo profile picture
Gwendolyn Botardo
6 days ago
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Dr. Santa Ana is very kind. He demonstrates advanced professional skill in the administration of regenerative medicine. The decompression and stem cell treatment provided for my hip pathology were executed with the highest level of competence. God bless Dr. JSA, and his staff: Heidi and Jennifer, thank you for your care and compassion. The CRNA who kept me comfortable and safely sedated- Amanda{?} - sorry if I forgot your name- a testimony to your great Versed execution. Alexus and Brie, thank you. CC: Cathy> appreciate how you easily share your peaceful zen and help to place those in your presence at ease. Awesome team! Thank you, All ; ) ~ GBS
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Evelyn Rose profile picture
Evelyn Rose
17 days ago
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My sister Benita Allen and I are patients of Dr. Robert Farhat. We just wanted to say how much we appreciate Dr. Farhat. He is patient, caring, and very thorough. We travel out of our way just to see him. His exceptional care and honesty are very refreshing. We trust him completely and would recommend him to anyone seeking pain management. The staff is also very professional and easy to work with.
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Peter Lynde profile picture
Peter Lynde
32 days ago
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Excellent experience with Dr. Farhat at the Michigan Center for Regenerative Medicine. Experienced, knowledgeable and patient. I highly recommend him and the Center.
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frank deblock profile picture
frank deblock
56 days ago
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Dr. Nemeth and Kelly are the kindest people. They understand and listen to what you have to say. I'm so glad he was able to get back to helping us with chronic pain.
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Cindy Jubeck profile picture
Cindy Jubeck
136 days ago
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Dr Nabity is one of the most caring, patient, & thorough doctors around! Highly recommended he & his team!
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Christopher Micakovic profile picture
Christopher Micakovic
153 days ago
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Dr. Farhat is knowledgeable, compassionate, and genuinely cares about helping patients improve their quality of life. The office is well organized, appointments are handled professionally, and the staff is always friendly and helpful.
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Tony Coy profile picture
Tony Coy
211 days ago
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Dr Nabity and his staff are great. They take the time to expansively listen and share knowledge about conditions, injuries, and treatments. I can tell Dr Nabity is passionate about helping his clients and avoiding surgery if possible. He’s clear about plan of action / plan of healing and that has helped me a lot! I feel more comfortable with my health and moving forward because of Michigan Center for Regenerative Medicine. I highly recommend.
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T Baugh profile picture
T Baugh
468 days ago
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Dr Farhat is the best when it comes to pain management. He is a doctor that actually listens and he truly cares about his patients. The staff goes above and beyond to help. Excellent medical team. I highly recommend!
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Judith Schwagle profile picture
Judith Schwagle
482 days ago
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Dr. Nabity is awesome! He spent over an hour with my husband and me going over my MRI’s for hip issues and all other information. He explained everything about PRP and answered all my questions. While we were there, he even checked out my husband’s hip problem too and gave him suggestions as well. I am very pleased with the plan of action we chose together. Looking forward to healing!!
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Patti Eisenbraun profile picture
Patti Eisenbraun
1130 days ago
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I found Dr. Santa Ana very helpful. I had a condition that is rarely seen and he did research on his own to make sure that I would receive the proper treatment. He’s very kind and his bedside manner is very spectacular. You can tell he really cares.
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Christopher Nofar profile picture
Christopher Nofar
1148 days ago
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Great experience, first time patient. Dr. Santa Ana was a pleasure to work with. Very informative, explained diagnoses and treatment plans at length, and walked me through my treatment step by step. Front office staff were pleasant and easy to work with. Looking forward to my future treatments.
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Patrick Medado profile picture
Patrick Medado
2212 days ago
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In an effort to use time at home towards bettering myself, I may have overdid it with the online workouts. I was able to get a telemedicine appointment with Dr. Santa Ana quickly and he was able to diagnose me online. His line of questioning showed me he was very knowledgeable and ultimately diagnosed me with a muscle strain which eased my fears. Great bedside manner. I highly recommended to anyone looking for genuine honesty and compassion in their care.
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Mark Rodriguez profile picture
Mark Rodriguez
3169 days ago
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Dr. checked up on me soon after the injection, and was notably concerned about my pain levels and well being. I would consider Dr. Nabity at the top of the list of cutting edge treatments, a caring bedside manner, and someone that I would recommend to anyone that I care about.
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In Their Words

We were amazed at how thorough the explanation of the recommended procedure was. I knew just what would happen and what I was agreeing to.

Steve G. Regenerative medicine patient

This doctor is very professional, using layman’s terms and taking his time with my parents to fully explain everything, and in answering all our questions!

Rosanna Windsor, Ontario · Family of a stem cell patient

Dr Nabity answered every question/concerns I had prior to the procedure in detail. If you leave a message for him he always calls you back himself.

Connie H. New Baltimore, MI · Stem cell patient

Excerpts from our patient testimonials.

Individual results vary. Reviews reflect each patient’s own experience.

A doctor in a white coat talks to an older male patient in an office.

Your visit

Your Path to Treatment

Most visits follow four simple steps. Our team guides you through each one and answers questions along the way.

1. Consultation

Meet your physician, talk through your symptoms, and review your history and goals.

2. Diagnosis & Imaging

Ultrasound or other imaging helps identify the source of your pain.

3. Treatment

If intraosseous treatment fits, your physician places it with x-ray guidance in an outpatient visit.

4. Follow-Up

Check-ins track your progress and adjust your plan as needed.

Insurance & cost

Insurance, Self-Pay, and Clear Pricing

We accept many major insurance plans for consultations, testing, and many spine and joint procedures. Regenerative treatments such as PRP and stem cell therapy are usually self-pay, so you get a clear estimate before you decide.

Usually billed to insurance

  • Consultations and office visits
  • EMG and nerve testing
  • Epidural, facet, and SI joint injections
  • Nerve blocks, radiofrequency ablation, and nerve stimulators

Usually self-pay

  • PRP and stem cell therapy (BMAC)
  • Prolotherapy
  • PRP hair restoration
  • Stem cell banking

Self-pay options include prompt-pay discounts, payment plans, and HSA or FSA funds for eligible expenses.

Plans we accept

  • PPO Trust

UMR coming soon. Blue Care Network plans require a referral. Coverage varies by plan and service, so call Rochester Hills (248) 216-1008 or Grand Rapids (616) 288-1109 and we will check your benefits.

Why patients choose Michigan Center for Regenerative Medicine

  • Board-certified physicians Every procedure is performed by a board-certified physician, not a technician.
  • Image-guided precision Ultrasound or fluoroscopic (x-ray) guidance places treatment exactly where it is needed.
  • Your own cells, prepared on site Platelets and bone marrow cells are processed in our in-house lab during your visit.
  • Results we track We have reported patient outcomes to the DataBiologics registry since 2019.
  • Clear, upfront pricing Itemized estimates before treatment, prompt-pay discounts, and payment plans.
  • Physicians who teach physicians Our doctors teach orthobiologic courses and helped write national back pain guidelines.

Our physicians

Meet Your Care Team

Thomas Nabity, MD, board-certified physician

Thomas Nabity, MD
Board-certified physician

John Santa Ana, DO, board-certified physician

John Santa Ana, DO
Board-certified physician

Robert Farhat, DO, board-certified physician

Robert Farhat, DO
Board-certified physician

Kevin M. Nemeth, MD, board-certified physician

Kevin M. Nemeth, MD
Board-certified physician

John Steele, MD, board-certified physician

John Steele, MD
Board-certified physician

Christopher Hannasch, DO, board-certified physician

Christopher Hannasch, DO
Board-certified physician

Credentials & memberships

Training You Can Look Up

Board certification shows a physician completed specialty training and passed independent exams. Our physicians go further, with added certifications and memberships in orthobiologics, musculoskeletal ultrasound and electrodiagnostic medicine. Each program is run by an independent organization, so you can see exactly what it requires.

PM&R Board Certification

Board certification in physical medicine and rehabilitation, the specialty focused on restoring function.

Pain Medicine Board Certification

Board certification in pain medicine, covering evaluation and treatment of complex pain conditions.

IOF Certification Courses

Advanced knee, hip and spine certification courses in image-guided orthobiologic procedures.

IOF Instructors & Training Hub

Our physicians teach other doctors as IOF instructors, and our Rochester Hills clinic hosts training.

Musculoskeletal Ultrasound

Certified in diagnostic musculoskeletal ultrasound, the imaging used to guide our treatments.

Electrodiagnostic Medicine

Board certification in electrodiagnostic medicine, the specialty behind EMG and nerve testing.

American Academy of PM&R

The national society for physiatrists, physicians focused on restoring movement.

Interventional Pain (ASIPP)

A society that sets education and practice standards for interventional pain medicine.

Orthopaedic Medicine (AAOM)

A physician group focused on non-surgical musculoskeletal care, including prolotherapy.

DataBiologics Registry

We report patient outcomes to a national orthobiologics registry to track results over time.

Patient stories

Hear From Our Patients

Patients describe their own experiences with care at the Michigan Center for Regenerative Medicine. Individual results vary.

Patient Testimonial

Patient Testimonial

FAQ

Intraosseous Treatment Questions

Answers to common questions about intraosseous treatment. Your physician can address your specific situation during a consultation.

What is intraosseous treatment?

Regenerative treatment placed into the joint and into the bone just beneath the cartilage.

Which joints are treated?

We currently use intraosseous treatment for the knee and hip.

Who is a candidate?

Often patients with more severe knee or hip osteoarthritis. Your physician reviews your imaging to decide.

Is it an outpatient procedure?

Yes. You go home the same day.

How is it guided?

Your physician uses x-ray guidance for precise placement.

What is recovery like?

Recovery is shorter than joint replacement surgery, with a period of limited weight bearing. Your physician will give you a plan.

Can it replace joint replacement surgery?

For some patients it may delay or avoid surgery. Others will still need a joint replacement.

What is placed in the bone?

Usually a concentrate of your own bone marrow cells. Your physician will explain the plan for you.

Is it covered by insurance?

Regenerative procedures are usually self-pay. Our team will give you cost information first.

How do I schedule a consultation?

Call (248) 216-1008 for Rochester Hills or (616) 288-1109 for Grand Rapids, or use the short form on this page.

Smiling senior doctor talking with a patient

Still Have Questions?

Talk with our team about your knee or hip arthritis.

Grand Rapids: (616) 288-1109
Rochester Hills: (248) 216-1008

Keep learning

Related Regenerative Medicine Articles

From a Torn Meniscus to the Kona Finish Line: Heather’s Ironman Story

After PRP for a torn meniscus, Heather trained for and finished the IRONMAN World Championship in Kona. Here is her comeback story.

Read the article

What Is Stem Cell Therapy and Could You Benefit From It?

Learn what stem cell therapy is, how bone marrow concentrate is used to support healing, which conditions it may help and how to find out if you are a candidate.

Read the article

A Nonsurgical Approach for Painful Joints with Prolotherapy

Prolotherapy is a nonsurgical injection treatment that aims to strengthen ligaments and tendons and relieve chronic joint pain. Learn how it works and who it may help.

Read the article

Next step

Find Out if Intraosseous Treatment Is Right for You

Answer a few short questions and our team will contact you to schedule a consultation.

Share your symptoms and goals in the short form.

Our team contacts you to schedule a consultation.

Meet a board-certified physician in Grand Rapids or Rochester Hills.

★ 4.7 Google ratingBoard-certified physiciansTwo Michigan clinics

Prefer to talk?Rochester Hills (248) 216-1008Grand Rapids (616) 288-1109

Free webinar replay

Watch: Intraosseous Treatment for Knee and Joint Pain

Watch the replay of our physicians’ webinar on intraosseous treatment for knee and joint pain.

Our physicians host free webinars with live Q&A. Watch any past webinar on demand, or call us to ask about the next date.

Our locations

Visit Our Michigan Clinics

Rochester Hills Clinic

355 Barclay Cir, Suite A
Rochester Hills, MI 48307

(248) 216-1008

Monday–Friday, 9:00 am–4:30 pm

Grand Rapids Clinic

1000 E. Paris Ave SE, Suite 221
Grand Rapids, MI 49546

(616) 288-1109

Monday–Friday, 9:00 am–4:30 pm

Areas we serve

Related Knee and Hip Care

Patients visit our Rochester Hills and Grand Rapids clinics from across Michigan.

Keep learning

Related Articles

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